منابع مشابه
Lung hyperinflation and flow limitation in chronic airway obstruction.
We reasoned that if flow limitation plays an important role in lung hyperinflation, then bronchodilatation should be associated with a decrease of functional residual capacity (FRC) only in subjects breathing under conditions of flow limitation. This hypothesis was tested in 33 subjects with chronic airway narrowing due to asthma or chronic obstructive pulmonary disease (COPD). Flow limitation ...
متن کاملExercise-induced flow limitation, dynamic hyperinflation and exercise capacity in patients with bronchial asthma.
It is known that, in stable asthmatics at rest, tidal expiratory flow limitation (EFL) and dynamic hyperinflation (DH) are seldom present. This study investigated whether stable asthmatics develop tidal EFL and DH during exercise with concurrent limitation of maximal exercise work rate (WRmax). A total of 20 asthmatics in a stable condition and aged 32+/-13 yrs (mean+/-SD) with a forced expirat...
متن کاملDynamic hyperinflation and flow limitation during methacholine-induced bronchoconstriction in asthma.
Although persistent activation of the inspiratory muscles and narrowing of the glottic aperture during expiration have been indicated as relevant mechanisms leading to dynamic hyperinflation in acute asthma, expiratory flow limitation (EFL) has recently been proposed as a possible triggering factor for increasing endexpiratory lung volume (EELV). To establish whether the attainment of maximal f...
متن کاملFlow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology.
Fashions in ideas, like clothes, come and go. From approximately 1950-1980, physiological research was seen as the key discipline in understanding lung disease and was at the cutting edge of pulmonary science. Subsequently, its importance has been down played amid a widely accepted but unfounded assumption that we now have a perfect working understanding of the physiological behaviour of the re...
متن کاملThe major limitation to exercise performance in COPD is dynamic hyperinflation.
[PDF] [Full Text] , August 1, 2008; 105 (2): 758-762. J Appl Physiol J. Butcher L. Nici, P. M. Calverley, H. R. Gosker, A. M. W. J. Schols, P. Palange, D. D. Marciniuk and S. J. B. West, P. D. Wagner, J. A. Neder, G. L. Scano, N. L. Jones, S. G. Zakynthinos, I. Vogiatzis, hyperinflation respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic The major limitation to exer...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2005
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.05.00009905